"It's all about "too much or too little" in the world of endocrinology. Barb discusses the hypothalamus and it's myriad of functions—sleep, sex, temperature regulation, onset of puberty, body rhythms, appetite, satiety, sexual orientation and more…Clinical correlations include drugs and the hypothalamus (aspirin, acetaminophen, diet pills, sleeping pills, gonadotropin-releasing hormones) as well as primary, secondary, and tertiary diseases of the hypothalamus. The hypothalamic-pituitary-target organ (thyroid, adrenal gland, gonads) axis will be discussed as well as clinical conditions involved with each target organ. Clinical conditions include hypopituitarism, hyper-and hypothyroidism, hyper-and hypoparathyroidism, Cushing's disease and Cushing's syndrome, Addison's disease, primary ovarian failure and primary testicular failure, polycystic ovary syndrome, endometriosis, cancers of the endocrine system, and dysfunction of the endocrine portion of the pancreas (hyperglycemia and hypoglycemia). The concept of negative feedback will also be discussed and correlated with various types of tests used to diagnose endocrine function and dysfunction. Barb will also discuss the treatment of all of the above conditions. Drugs to be discussed include the various hormonal therapies for endocrine cancers, the types of glucocorticoids and their potency profile, metformin, levothyroxine, androgen, and estrogen replacement therapies." -- Barb Bancroft website.